As the NCAA Tournament moves into the second week/end, fans and analysts alike turn their attention to the top contenders in the race to title. This year’s Sweet 16 features a myriad of teams, each showcasing unique strengths and competitive edges. From defensive powerhouses to offensive juggernauts, the tournament promises excitement and intense matchups. Here’s a look at the top 10 teams making a splash in this year’s tournament, and why they’re considered the best bets because there isn’t one true Cinderella left in this year’s Big Dance.

10. Texas Tech Red Raiders

Texas Tech Red Raiders head coach Grant McCasland in the second half of a first round men’s NCAA Tournament game against the North Carolina-Wilmington Seahawks at Intrust Bank Arena on March 20, 2025, Wichita, Kan.
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Texas Tech, a No. 3 seed in the West Region, is favored for their strong defensive capabilities and athleticism. They advanced with victories over UNC Wilmington and Drake, featuring standout performances from JT Toppin and Elijah Hawkins. Their athleticism and defense make them a formidable opponent in the Sweet 16.

9. Purdue Boilermakers

Purdue Boilermakers guard Braden Smith (3) and guard Gicarri Harris (24) celebrate after a play during the second half of a second round men’s NCAA Tournament game against the McNeese State Cowboys at Amica Mutual Pavilion on March 22, 2025, in Providence, R.I.
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The Purdue Boilermakers, a No. 4 seed in the Midwest Region, demonstrate consistent performance driven by strong offense led by Trey Kaufman-Renn and Braden Smith. With a 24-11 record, Purdue has shown resilience in advancing to the Sweet 16 amidst rebuilding this season.

8. Alabama Crimson Tide

Alabama Crimson Tide guard Mark Sears (1) celebrates with teammates after making the game winning shot to beat the Auburn Tigers in overtime at Neville Arena on March 8, 2025, in Auburn, Ala.
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Alabama Crimson Tide boasts a robust offense and deep roster, having overcome Robert Morris with key contributions from Mark Sears. Their depth and tempo management have been crucial in recent matches, setting them up as strong contenders for the Sweet 16 advancement.

7. Kentucky Wildcats

Kentucky head coach Mark Pope yells to his team as they face Alabama during the first half of a Southeastern Conference tournament quarterfinal game at Bridgestone Arena in Nashville, Tenn., on Friday, March 14, 2025.
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The Kentucky Wildcats, a No. 3 seed in the Midwest Region, boast a rich basketball legacy and talented roster. Their strong fan base and experienced players position them as favorites to advance, making them a team to watch in the Sweet 16.

6. Tennessee Volunteers

Tennessee Volunteers guard Chaz Lanier grabs a pass during practice at Rupp Arena on March 19, 2025, in Lexington, Ky.
Jordan Prather-Imagn Images

The Tennessee Volunteers, a No. 2 seed in the Midwest Region, are favored to beat Kentucky, despite Kentucky freshman Lamon Butler’s comments, due to their robust defense and physical gameplay style. Their aggressive approach often disrupts opponents, making them a formidable force in the tournament.

5. Michigan State Spartans

Michigan State guard Jase Richardson talks to head coach Tom Izzo before a play against Wisconsin during the first half of a Big Ten Tournament semifinal at Gainbridge Fieldhouse in Indianapolis, on Saturday, March 15, 2025.
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The Michigan State Spartans, with 27 consecutive NCAA Tournament appearances, are known for their experience and toughness. As a No. 2 seed, they face New Mexico after a decisive 87-62 win over Bryant. Their balanced offense and strong rebounding make them a formidable opponent in the tournament.

4. Duke Blue Devils

Duke Blue Devils center Khaman Maluach (9), forward Cooper Flagg (2) and guard Isaiah Evans (3) celebrate on the bench during the second half against the Mount St. Mary’s Mountaineers in the first round of the NCAA Tournament at Lenovo Center on March 21, 2025, in Raleigh, N.C.
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The Duke Blue Devils, a No. 1 seed in the East, are dominating with a 33-3 record. Led by stars Tyrese Proctor and Cooper Flagg, Duke has won its first two NCAA tournament games by a combined 67 points, showcasing their potential for a championship run.

3. Houston Cougars

Houston Cougars head coach Kelvin Sampson talks with his players during a game against the UCF Knights at Fertitta Center on Jan. 20, 2024, in Houston..
Troy Taormina-USA TODAY Sports

Kelvin Sampson’s team is the No. 1 seed in the Midwest Region and the Cougars have been consistently great all season and they have an experienced roster. The Cougars recently beat Gonzaga 81-76, showcasing their defensive prowess and offense led by LJ Cryer. They’ll face Purdue in the Sweet 16.

2. Florida Gators

Florida Gators guard Walter Clayton Jr. (1), Florida Gators center Rueben Chinyelu (9) and Florida Gators head coach Todd Golden clap after a game against the Mississippi Rebels at Exactech Arena at the Stephen C. O’Connell Center on March 8, 2025, Gainesville, Fla.
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The Florida Gators lead the West Region as the No. 1 seed, boasting a well-rounded team with impressive offensive and defensive capabilities. Guard Walter Clayton Jr. shines, having recently been the first first-team All-American in Florida history. His dynamic play makes the Gators a strong contender moving forward.

1. Auburn Tigers

Auburn head coach Bruce Pearl and his No.1 Tigers celebrate after 94-78 win over Kentucky — the first win at Rupp Arena since 1988 in SEC basketball Saturday afternoon in Lexington, Kentucky March 1, 2025.
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The Auburn Tigers, 2025’s top overall seed, boast a strong offense and defense. Led by Johni Broome, they excel in both efficiency metrics, with a notable 16-5 record in Quad 1 games, making them a formidable contender in the South Region.

Conclusion

Michigan State Spartans guard Jase Richardson (11) celebrates a made basket in the second half against the Oregon Ducks at Gainbridge Fieldhouse on March 14, 2025, in Indianapolis.
Trevor Ruszkowski-Imagn Images

As the Sweet 16 stage unfolds, these teams have demonstrated the grit and skill required to potentially clinch the championship title. While each team brings its unique strengths, only one can emerge as the victor. With intense basketball action and high stakes, fans can expect thrilling performances and unforgettable moments. As the tournament progresses, one thing remains clear: these top teams are ready to leave their mark and vie for the ultimate prize in college basketball.